Aim and Scope
The meeting is focused on the comparative view of problems and solutions related to recombinant proteins production across different and always expanding potential hosts, with special emphasis in comparative physiology. Over the previous meetings, this topic has steadily attracted an increasing number of researchers from both academia and bio-industry, who face continuous new challenges in this area, e.g. in structural genomics (exponential increase in the cell factories requirements in terms of protein quality, capacity for efficient protein complexes production etc).
This meeting is aimed to provide a forum for discussion on the basic cell biological principles that underlie the interactions between cell physiology/function, environmental conditions and, cellular protein production processes. In particular, Sessions topics will focus on newly identified host cell responses to protein production, new insights on protein quality control and the main bottlenecks in protein production such as folding and proteolytic degradation.  The scope of these sessions will be geared towards the understanding on how to manipulate cell functions as well as to develop new tools and devices for protein production. In addition, a number of specific workshops will be designed to focus on the industrial aspects of protein production, improved gene expression vectors and strategies, and tools to acquire useful physiological data (including systems biology platforms). The meeting will cover the wide diversity of microbial systems used as cell factories, broadening the scope to higher eukaryotic systems such as mammalian and plant cells.
Importantly, the number of registrants will be restricted to 200~230.We are looking forward to provide a friendly Mediterranean atmosphere in Barcelona to make headway in the field of recombinant protein production, combining both fundamental sciences with applied approaches.
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